Elastase 弹性蛋白酶 >3U/mg

cas:39445-21-1

Source: Porcine Pancreas

I.U.B.: 3.4.21.36

Porcine pancreatic elastase has a molecular weight of 25.9 kDa, and a pH optimum of 8.5.  While elastase will hydrolyze a wide variety of protein substrates, it is unique among proteases in its ability to hydrolyze native elastin, a substrate not attacked by trypsin, chymotrypsin or pepsin. Soybean trypsin inhibitor and kallikrein inhibitor suppress proteolytic but not elastolytic activity.  Elastase is assayed using a method adapted from that of Feinstein et al., Biochem. Biophys. Res. Comm., 50, 1020 (1973) and using the more soluble substrate of Bieth et al., Biochem. Med., 11, 350 (1974).