MASP1 Pre-design Chimera RNAi
产品名称: MASP1 Pre-design Chimera RNAi
英文名称: MASP1 Pre-design Chimera RNAi
产品编号: H00005648-R03
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_139125
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 5648
- Gene Name:
- MASP1
- Gene Alias:
- CRARF,CRARF1,DKFZp686I01199,FLJ26383,MASP,MGC126283,MGC126284,PRSS5,RaRF
- Gene Description:
- mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Omim ID:
- 600521
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in multiple transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Two of the isoforms are cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq
- Other Designations:
- Ra-reactive factor serine protease p100,manan-binding lectin serine protease-1,mannan-binding lectin serine protease 1,mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor),mannan-binding lectin serine protease 1, isof
- Gene Pathway
- Related Disease
- Birth Weight
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Inflammation
- Leukemia
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Macular Degeneration
- Meningeal Neoplasms
- Meningioma
- Pulmonary Disease, Chronic Obstructive
- Sepsis
- Syndrome
- Urinary Bladder Neoplasms
- Werner syndrome