Knockout™ Serum Replacement (Knockout™ SR) is a defined, serum-free formulation optimized to grow and maintain undifferentiated ES cells in culture (1). It directly replaces FBS in existing protocols. The performance of Knockout™ SR is enhanced when used with Knockout™ D-MEM. Product performance is confirmed by evaluation of its ability to support the growth of undifferentiated D3 ES cell colonies on inactivated mouse embryonic fibroblasts.

We also offer the KnockOut™ ESC/iPSC Media Kit, an entire media system for feeder-based culture of pluripotent stem cells in one product.