PeproTech重组小鼠IL-36RA 25ug
产品名称: PeproTech重组小鼠IL-36RA 25ug
英文名称: Murine IL-36RA
产品编号: 210-36RA-25
产品价格: 0
产品产地: 美国
品牌商标: PeproTech(派普泰克)
更新时间: null
使用范围: null
美国PeproTech(派普泰克)公司中国代表处
- 联系人 :
- 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
- 邮编 : 215123
- 所在区域 : 江苏
- 电话 :
- 传真 : 0512-68325993
- 邮箱 : peprotech.infochina@thermofisher.com
Description: The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-κB signaling induced by either IL-36α, β or γ by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant Murine IL-36RA is anE.coli-derived 16.9 kDa protein containing 154 amino acid residues. Source:E.coli Synonyms:Interleukin-36RA, FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta AA Sequence:VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses. Biological Activity:Measured by its ability to inhibit secretion of IL-8 by A431 cells in the presence of human IL-36γ. Country Of Origin:USA Research Use Only: Not for use in diagnostic or therapeutic procedures.