内毒素:
Less than 0.01 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:
Immobilized Anti-Human LAG3 MAb, Human IgG1 at 2μg/mL (100 μL/well) can bind Human LAG-3, His Tag, low endotoxin (Cat. No. LA3-H522a) with a linear range of 1-6 ng/mL (QC tested).

产品背景:
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

产品描述:
This protein carries a polyhistidine tag at the C-terminus, and has a calculated MW of 47.1 kDa. The predicted N-terminus is Leu 23. The reducing (R) protein migrates as 55-60 kDa in SDS-PAGE due to glycosylation.
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