内毒素:
Less than 0.01 EU per μg by the LAL method.

纯度:
>95% as determined by SDS-PAGE.

活性:
Immobilized Human Mesothelin, His Tag, low endotoxin (Cat. No. MSN-H522a) at 2 μg/mL (100 μL/well) can bind Anti-MSLN MAb, Human IgG1 with a linear range of 0.1-3 ng/mL (QC tested).

产品背景:
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

产品描述:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.0 kDa. The protein migrates as 32-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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