重组人VCC-1/CXCL17-蛋白检测-试剂-生物在线
重组人VCC-1/CXCL17

重组人VCC-1/CXCL17

商家询价

产品名称: 重组人VCC-1/CXCL17

英文名称: Recombinant Human VEGF Co-regulated Chemokine 1/CXCL17 (rHuVCC-1/CXCL17)

产品编号: HZ640035

产品价格: 0

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: null

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 重组人VCC-1/CXCL17

附带条件

特技

CXC17也被命名为树突状细胞和单核细胞趋化因子样蛋白(DMC)和VEGF共调节趋化因子1(Vcc-1),是属于CXC趋化因子家族的一种小细胞因子。它在肺组织中表达,并可在气管、胃和骨骼肌中检测到。CXC17吸引树突状细胞和单核细胞,并在肿瘤中受到调控。它可能是一种管家趋化因子,调节未激活的血单核细胞和未成熟树突状细胞的组织进入,并可能在先天性防御感染中发挥作用。成熟的人CXC17分别与牛、小鼠和大鼠CXCL17共有73%、71%和64%氨基酸序列同一性。

附带条件

该材料由Sangon生物技术公司提供,用于研究、实验室或进一步评估目的。不适合人类使用。

附带条件

物理外观无菌过滤白冻干(冻干)粉末。

纯度为96%以上,采用SDS-PAGE和HPLC分析。

来源大肠杆菌。

与标准相比,生物活性完全具有生物活性。用小鼠内皮细胞诱导VEGF表达的ED50小于5μg/ml,对应于200 IU/mg的特异性活性。

用0.2μm过滤的浓缩液在pH 7.4的PBS中,用3%海藻糖冻干。

LaAl法测定rHUVCC-1/CXC17的内毒素低于0.1 EU/μg。

我们建议在打开之前将这个小瓶简单地离心,以将内容物带到底部。在含0.1% BSA的无菌蒸馏水或含水缓冲液中重组,浓度为0.1-1.0mg/mL。原料溶液应分摊到工作等分试样中,并储存在小于20℃的温度下,应在适当的缓冲溶液中进一步稀释。

 

AAA序列SSLNPGVARG HRDGGQASRR WLQGEGQEQR CKDWFRAPR RKFMTVSGLPG-KKQCPCDHFK GNVKTrHTQR HHKPKNKHSR ACQQFLQQCQ LRSPHARPL

产品描述

概述

 

CXCL17 also named dendritic cell and monocyte chemokine-like protein (DMC) and VEGF co-regulated chemokine 1 (VCC-1), is a small cytokine belonging to the CXC chemokine family. It is constitutively expressed in the lung and can be detected in trachea, stomach and skeletal muscle. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It may be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues and may play a role in the innate defense against infections. Mature human CXCL17 shares 73 %, 71 % and 64 % amino acid sequence identity with bovine, mouse and rat CXCL17, respectively.

使用说明

 

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

 

 

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 96 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/mg.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 3 % Trehalose.
Endotoxin Less than 0.1 EU/μg of rHuVCC-1/CXCL17 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL