PeproTech重组人VEGF-C-细胞/细菌培养-试剂-生物在线
PeproTech重组人VEGF-C

PeproTech重组人VEGF-C

商家询价

产品名称: PeproTech重组人VEGF-C

英文名称: Recombinant Human VEGF-C

产品编号: 100-20CD

产品价格: 0

产品产地: 美国

品牌商标: PeproTech(派普泰克)

更新时间: 2023-09-20T15:34:30

使用范围: null

美国PeproTech(派普泰克)公司中国代表处
  • 联系人 :
  • 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
  • 邮编 : 215123
  • 所在区域 : 江苏
  • 电话 :
  • 传真 : 0512-68325993
  • 邮箱 : peprotech.infochina@thermofisher.com

Recombinant Human VEGF-C

Product Details

Catalog Number:100-20CD
Description:

VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated, non-covalent, disulfide-linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions.

*As of January 30, 2019 Human VEGF-C (Catalog Number 100-20CD) will be replacing Human VEGF-C (Catalog Number 100-20C)

Source:HEK293 cells

Synonyms:Vascular Endothelial Growth Factor-C, VRP, Flt4 ligand

AA Sequence (monomer):AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR

Purity:≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions.