PeproTech重组人VEGF-C
产品名称: PeproTech重组人VEGF-C
英文名称: Recombinant Human VEGF-C
产品编号: 100-20CD
产品价格: 0
产品产地: 美国
品牌商标: PeproTech(派普泰克)
更新时间: 2023-09-20T15:34:30
使用范围: null
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Recombinant Human VEGF-C
Product Details
Catalog Number:100-20CDDescription:VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated, non-covalent, disulfide-linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions.
*As of January 30, 2019 Human VEGF-C (Catalog Number 100-20CD) will be replacing Human VEGF-C (Catalog Number 100-20C)
Source:HEK293 cells
Synonyms:Vascular Endothelial Growth Factor-C, VRP, Flt4 ligand
AA Sequence (monomer):AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
Purity:≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions.