IWP-4-干细胞-试剂-生物在线
IWP-4

IWP-4

商家询价

产品名称: IWP-4

英文名称: IWP-4

产品编号: SM-0004-0005

产品价格: 0

产品产地: 以色列

品牌商标: Biological industries(BI)

更新时间: null

使用范围: null

上海逍鹏生物科技有限公司
  • 联系人 : 市场部
  • 地址 : 上海市浦东新区祖冲之路1505弄80号1幢3楼
  • 邮编 : 200120
  • 所在区域 : 上海
  • 电话 : 189****5545
  • 传真 : 021-58777053
  • 邮箱 : Never.huang@xpbiomed.com

 

Product Description

IWP-4 is an inhibitor of the Wnt pathway, specifically targeting membrane-bound O-acyltransferase porcupine (PORCN) with an IC50 of 25 nM. IWP-4 has been an effective component within differentiation protocols of pluripotent stem cells (PSCs) into functional cardiomyocytes when combined with CHIR99021 (Cat. No. SM-0001-0010), IWP-2 (Cat. No. SM-0003-0010), Activin A, bFGF, and BMP4 (Lian, et al.), as well as in suspension cultures for cardiac differentiation from human PSCs (Chen, et al.). IWP-4 precisely induces expression of myosin light chain in both atrial and ventricular forms for the creation of primitive cardiomyocytes from human embryonic stem cells (ESCs) (Hudson, et al.). 
 

Product Synonyms:

IWP 4, Inhibitor of WNT Production-4

Constructed from renowned protocols, Biological Industries selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.

 产品官网链接:https://www.bioind.com/worldwide/iwp-4/

想了解更多种类的小分子,请点击官网:https://www.bioind.com/worldwide/products/stem-cell-research/small-molecules/