Immune checkpoint pathway is a focal point of today’s cancer research. CD47 is one of the best characterized checkpoint proteins. CD47 binding to SIRP alpha aids in tumor evasion of the immune system. Therefore, the pharmaceutical inhibition of CD47 has been considered a promising strategy by many oncologists.
Application
This pair is useful for screening for inhibitors of human CD47 binding to human SIRP alpha. 
Reconstitution
See Certificate of Analysis for details of reconstitution instruction and specific concentration. 
Storage
 Upon receipt, please store all items at -70℃.
After reconstitution, the stock solution should be kept at -70℃.