表皮生长因子 人类-常用生化试剂-试剂-生物在线
表皮生长因子 人类

表皮生长因子 人类

商家询价

产品名称: 表皮生长因子 人类

英文名称: Epidermal Growth Factor human EGF

产品编号: E9644

产品价格: 0

产品产地: Sigma aldrich

品牌商标: Sigma aldrich

更新时间: null

使用范围: null

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 基本信息

价格与库存

货号与规格 库存   价格 (RMB) 数量    

E9644-.2MG

 

需要从国外调货 Estimated Delivery Date 2-3周

 

4,752.54

 

产品名称

Frequently Asked Questions

Live Chat and Frequently Asked Questions are available for this Product.

Analysis Note

≥98% SDS-PAGE

Biochem/physiol Actions

Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

Application

Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

General description

Epidermal Growth Factor (EGF) is a small mitogenic polypeptide which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is structurally homologous to human transforming growth factor-α (TGF-alpha), and both exert their actions through EGF receptors. EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells.

EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

法律信息

LONG 注册商标 Novozymes Gropep Limited

Other Notes

The biological activity of recombinant, human EGF is measured by its ability to stimulate the mouse fibroblast cell line, BALB/3T3. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.

性质

Related Categories Cancer ResearchCell BiologyCell CultureCell Signaling and NeuroscienceCore Bioreagents,
Quality Level   PREMIUM
recombinant   expressed in E. coli
assay   ≥97% (SDS-PAGE)
form   lyophilized powder
potency   0.08-0.8 ng/mL ED50/EC50
impurities   ≤1 EU/μg endotoxin(EGF)
suitability   suitable for cell culture
storage temp.   −20°C
Gene Information   human ... EGF(1950)