上海复蒙基因生物科技有限公司是美国Sciencell公司官网公布的一级代理商：

    美国ScienCell研究实验室（www.sciencellonline.com）成立于1999年，公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发，在全球拥有众多客户。在国内销售8年来，很多老师应用其产品发表了高质量的SCI文章，且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质，深受广大科研工作者的信赖。
         ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。
 

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人子宫肌层的微血管内皮细胞：

Description
Myometrial microvascular endothelial cells (MMEC) are located in the myometrium between the endometrium and the serosa of the uterus and exhibit typical cobblestone morphology. During pregnancy, angiogenesis occurs through MMEC proliferation in order to support the hypertrophy of the myometrial smooth muscle cell layer [1]. Significant evidence also indicates that endothelial cell dysfunction in the myometrium may contribute to the development of preeclampsia [2]. In addition, MMEC proliferation and angiogenesis may play a role in the formation of leiomyomata [2]. Studies have shown that MMEC express the oxytocin receptor, which may promote vasodilation in the microvasculature of the myometrium [3]. Human MMEC are a useful in vitro model to elucidate the mechanisms of angiogenesis and to develop treatments for female reproductive tract disorders.

HMMEC from ScienCell Research Laboratories are isolated from human uterus. HMMEC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HMMEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and CD31 (PECAM), and by uptake of DiI-Ac-LDL. HMMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HMMEC are guaranteed to further expand for 10 population doublings under the conditions provided by ScienCell Research Laboratories.

Recommended Medium
It is recommended to use Endothelial Cell Medium (ECM, Cat. #1001) for culturing HMMEC in vitro.

Product Use
HMMEC are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.

Storage
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.

Shipping
Dry ice.

Reference
[1] Gargett C, Bucak K, Rogers P. (2000) “Isolation, characterization and long-term culture of human myometrial microvascular endothelial cells.” Hum Reprod. 15(2): 293-301.
[2] Hayman R, Brockelsby J, Kenny L, Baker P. (1999) “Preeclampsia: the endothelium, circulating factor(s) and vascular endothelial growth factor.” J So Gynecol Investig. 6(1): 3-10.
[3] Weston G, Cann L, Rogers P. (2003) “Myometrial microvascular endothelial cells express oxytocin receptor.” BJOG. 110(2):149-156.

Sciencell公司其它产品：
 

原代细胞（纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离。）
原代细胞专用培养基
无血清培养
干细胞无血清培养基（骨髓间充质干细胞、胚胎干细胞）
原代细胞转染试剂盒等。

        复蒙基因|FMGBio(www.fmgbio.com/   www.sciencell-sh.com/   )成立于2005年， 是专业从事牛血清生产、销售高端的原代细胞类科研产品。这些产品从根本上提高了全球生命医学研究、人类重要疾病药物研发、新药研发的成功率。近几年的新药研发成功率在逐年下降，其根本原因之一就是传统的药物筛选系统是建立在只具有30-40%人类基因群的一系列细胞株上。这样一个有“缺陷型”药物筛选系统所产生的药物用于人体上就会出现许多致命的弱点和不完整性。新一代药物筛选系统是含有一系列近乎完整的人类基因群的原代细胞株。而利用这些原代细胞株所甄别和筛选出来的候选药物，其诊治人类疾病的成功几率将大大增加。这样不但大大节省了新药的开发成本，而且将极大地提高人类的健康质量。

        复蒙基因|FMGBio现有的产品：美国Sciencell（原代细胞、原代细胞专用培养基、无血清培养基）、3D Bioteck（三维细胞培养支架）、年产1000万毫升的内蒙古牛血清生产基地等。

       复蒙基因|FMGBio的PI团队已经发展到专职PI 20人，联席PI 312人，其中大多数拥有海外背景。截止到2009年3月，以PI或联席PI为第一作者发表SCI 论文1682 篇（总IF 值为5721.82，其中影响因子IF>5.0 的论文216 篇，IF>10.0论文32 篇）。

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