CINC-2α/CXCL3, Rat-细胞/细菌培养-试剂-生物在线
CINC-2α/CXCL3, Rat

CINC-2α/CXCL3, Rat

商家询价

产品名称: CINC-2α/CXCL3, Rat

英文名称:

产品编号: CB055-0992

产品价格: 0

产品产地: 美国

品牌商标: ExCell Bio

更新时间: null

使用范围: null

上海吉泰依科赛生物科技有限公司
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Chemokine (C-X-C motif) ligand 3 (CXCL3)  is a small cytokine belonging to the CXC chemokine family that is also known as MIP2β (macrophage inflammatory protein 2 beta), or DCIP1 (dendritic cell inflammatory protein1) in mouse, CINC-2 (cytokineinduced neutrophil attractant 2) in rat, or GROγ (growthregulated oncogene gamma) in human. 
CXCL3 controls migration and adhesion of monocytes and mediates its effects on target cells by interacting with the cell surface chemokine receptor CXCR2. It has been shown that CXCL3 regulates cerebellar granule neuron precursors toward the internal layers of the cerebellum during cerebellum morphogenesis. CXCL3 is a potential target for medulloblastoma therapy. CXCL3 is regulated transcriptionally by BTG2.
Recombinant Rat CINC-2α/CXCL3 produced in CHO cells is a polypeptide chain containing 68 amino acids. A fully biologically active molecule, rrCINC-2α/CXCL3 has a molecular mass of 7.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at ExCell Bio.