人直肠成纤维细胞-细胞株/菌种-试剂-生物在线
人直肠成纤维细胞

人直肠成纤维细胞

商家询价

产品名称: 人直肠成纤维细胞

英文名称: HRecF

产品编号: 2960

产品价格: 0

产品产地: 美国

品牌商标: sciencell

更新时间: 2024-03-27T09:05:42

使用范围: null

上海中乔新舟生物科技有限公司
  • 联系人 : 胡小姐
  • 地址 : 上海市宝山区长江南路180号A区401-406室
  • 邮编 : 200433
  • 所在区域 : 上海
  • 电话 : 181****0148
  • 传真 : 021-56760351
  • 邮箱 : wwwfudan@163.com;hufangqiong@zqxzbio.com

 产品名称:人直肠成纤维细胞


货号:2960
 

The human rectum is located in the lower gastrointestinal tract and functions as a temporary storage site for fecal material. Rectal fibroblasts are important structural components of the rectum and are implicated in a number of diseases including ulcerative colitis, Crohn’s disease, and rectal cancer. Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. The main functions of fibroblasts are to maintain the structural integrity of connective tissue and to aid in tissue repair and remodeling [1, 2]. Studies have shown that functional changes to human rectal fibroblasts (HRecF) can impair wound healing and affect epithelial cell proliferation in ulcerative colitis patients [3]. In Crohn’s disease, HRecF respond to intestinal inflammation by proliferating abnormally, which leads to fibrotic scarring. Primary HRecF can be used to study the pathophysiology of rectal cancer, ulcerative colitis, and Crohn’s disease and to help develop therapies for these diseases.

HRecF from ScienCell Research Laboratories are isolated from human rectum. HRecF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HRecF are characterized by immunofluorescence with antibody specific to fibronectin. HRecF are negative for mycoplasma, bacteria, yeast, and fungi. HRecF are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Fibroblast Medium (FM, Cat. #2301) for culturing HRecF in vitro.