PeproTech重组人 IL-37 (IL-1F7)(Animal Free)500ug-细胞/细菌培养-试剂-生物在线
PeproTech重组人 IL-37 (IL-1F7)(Animal Free)500ug

PeproTech重组人 IL-37 (IL-1F7)(Animal Free)500ug

商家询价

产品名称: PeproTech重组人 IL-37 (IL-1F7)(Animal Free)500ug

英文名称: Human IL-37 (IL-1F7)

产品编号: AF-200-39

产品价格: 0

产品产地: 美国

品牌商标: PeproTech

更新时间: null

使用范围: null

美国PeproTech(派普泰克)公司中国代表处
  • 联系人 :
  • 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
  • 邮编 : 215123
  • 所在区域 : 江苏
  • 电话 :
  • 传真 : 0512-68325993
  • 邮箱 : peprotech.infochina@thermofisher.com

 

Animal-Free Recombinant Human IL-37 (IL-1F7)

Catalog Number:
AF-200-39
Synonyms:
Interleukin-37, IL-1F7, IL-1ζ (zeta), IL-1H4
Description:
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-37 (IL-1F7), which acts as a modulator of the immune response. Reduction of IL-37 synthesis in PBMCs leads to increased production of proinflammatory cytokines including IL-1 alpha, IL-1 beta, IL-6 and TNF- alpha. The role of IL-37 as an inhibitor of the innate inflammatory response is also corroborated by the observation that it is highly expressed in synovial tissue from patients with rheumatoid arthritis. Full length IL-37 resides primarily in the cytoplasm, but after activation through cleavage by CASP1, it can translocate to the nucleus where it exerts its activity by direct interaction with SMAD3. Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37. Manufactured using all Animal-Free reagents.
AA Sequence:
MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.
 
 
 
 
Research Interests:
 
 
Country of Origin:
USA