人全长(HIV-2 gp36)重组蛋白-蛋白质/抗原/多肽-试剂-生物在线
人全长(HIV-2 gp36)重组蛋白

人全长(HIV-2 gp36)重组蛋白

商家询价

产品名称: 人全长(HIV-2 gp36)重组蛋白

英文名称: Recombinant HIV-2 gp36 (390-702)

产品编号: HZHIV-139

产品价格: 0

产品产地: 美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: null

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人全长(HIV-2 gp36)重组蛋白

背景资料 HIV-1 and HIV-2 appear to package their RNA differently. HIV-1 binds to any appropriate RNA whereas HIV-2 preferentially binds to mRNA which creates the Gag protein itself. This means that HIV-1 is better able to mutate. HIV-2 is transmitted in the same ways as HIV-1: Through exposure to bodily fluids such as blood, semen, tears and vaginal fluids. Immunodeficiency develops more slowly with HIV-2.
HIV-2 is less infectious in the early stages of the virus than with HIV-1.
The infectiousness of HIV-2 increases as the virus progresses.
Major differences include reduced pathogenicity of HIV-2 relative to HIV-1, enhanced immune control of HIV-2 infection and often some degree of CD4-independence. Despite considerable sequence and phenotypic differences between HIV-1 and 2 envelopes, structurally they are quite similar. Both membrane-anchored proteins eventually form the 6-helix bundles from the N-terminal and C-terminal regions of the ectodomain, which is common to many viral and cellular fusion proteins and which seems to drive fusion.
HIV-1 gp41 helical regions can form more stable 6-helix bundles than HIV-2 gp41 helical regions however HIV-2 fusion occurs at a lower threshold temperature (25°C), does not require Ca2+ in the medium, is insensitive to treatment of target cells with cytochalasin B, and is not affected by target membrane glycosphingolipid composition.
人全长(HIV-2 gp36)重组蛋白产品描述 HIV-2 gp36 34 kDa recombinant- contains the sequence of HIV-2 envelope immunodominant regions gp36, amino acids 390-702. The protein is fused to beta-galactosidase (114 kDa) at N-terminus.
来源宿主 大肠杆菌中重组表达
序列
 
溶解建议 提供的重组HIV-2 gp36 (390-702)产品为无菌的无色透明溶液形式.该产品已溶解在含0.01M Na2CO3, 0.01M Na3EDTA, 0.014 甲基巯基乙醇, 0.02% 十二烷基肌氨酸钠溶液.
人全长(HIV-2 gp36)重组蛋白保存建议 Protein should be stored at 4℃. Refrigerate Upon arrival. DO NOT FREEZE.