重组人PTH1-84-蛋白检测-试剂-生物在线
重组人PTH1-84

重组人PTH1-84

商家询价

产品名称: 重组人PTH1-84

英文名称: Recombinant Human Parathyroid Hormone 1-84

产品编号: HZ600084

产品价格: 0

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: null

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 重组人PTH1-84

附带条件

特技

甲状旁腺素(PTH)是一个含有84个氨基酸的多肽。它是调节甲状旁腺分泌Ca2+稳态的关键,通过激活成骨细胞和抑制破骨细胞,促进钙从骨释放到细胞外液,间接促进钙的肠吸收,促进钙的吸收。肾小管重吸收钙和增加肾排泄磷酸盐。它是骨代谢的主要调节因子。当细胞外液中钙水平较低时,甲状旁腺分泌增加。

附带条件

该材料由Sangon生物技术公司提供,用于研究、实验室或进一步评估目的。不适合人类使用。

附带条件

物理外观无菌过滤白冻干(冻干)粉末。

纯度为97%以上,采用SDS-PAGE和HPLC分析。

来源大肠杆菌。

与标准相比,生物活性完全具有生物活性。通过诱导小鼠MC3T3E1细胞cAMP积聚的能力,ED50小于50 ng/ml,对应于2×104 IU/mg的特异性活性。

用0.2μm过滤浓缩液在pH 7.4的PBS中进行冻干。

LaAl法测定内毒素低于1 EU /μg的RuPHT1-41。

我们建议在打开之前将这个小瓶简单地离心,以将内容物带到底部。在含0.1% BSA的无菌蒸馏水或含水缓冲液中重组,浓度为0.1-1.0mg/mL。原料溶液应分摊到工作等分试样中,并储存在小于20℃的温度下,应在适当的缓冲溶液中进一步稀释。

 

AAA序列SvSEIQLMHN LGKHLNSMER VWLRKLQDD VHNFKALGAP

产品描述

概述

 

Parathyroid hormone (PTH) is a single polypeptide of 84 amino acids. It is a critical hormone in the regulation of Ca2+ homeostasis and secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.

使用说明

 

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

 

 

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 97 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Endotoxin Less than 1 EU/μg of rHuPTH1-84 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNFVALGAP LAPRDAGSQR PRKKEDNVLV ESHEKSLGEA DKADVNVLTK AKSQ