重组小鼠Bcl-xL-蛋白检测-试剂-生物在线
重组小鼠Bcl-xL

重组小鼠Bcl-xL

商家询价

产品名称: 重组小鼠Bcl-xL

英文名称: Recombinant Murine B-cell lymphoma-extra large

产品编号: HZ

产品价格: 0

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: null

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 重组小鼠Bcl-xL

附带条件

特技

Bcl-XL是一种跨膜蛋白,位于长寿命和有丝分裂后的细胞线粒体膜中,如脑细胞。它在Fas配体的信号转导通路中发挥作用。Bcl xL是抗凋亡蛋白,是Bcl-2家族的成员,能够形成异源二聚体,这是调控细胞凋亡的重要事件。它与癌细胞的存活有关。Bcl xL是凋亡/活性细胞**的主要监测者。它具有细胞死亡阻遏活性,因此作为生存蛋白。小鼠Bcl-xL分别与人和大鼠Bcl-xL共有97%和99% A.A.序列同源性。

附带条件

该材料由Sangon生物技术公司提供,用于研究、实验室或进一步评估目的。不适合人类使用。

附带条件

物理外观无菌过滤白冻干(冻干)粉末。

纯度为97%以上,采用SDS-PAGE和HPLC分析。

来源大肠杆菌。

生物活性试验。

在2μPBS、pH 7.4、5%海藻糖中用0.2μm过滤浓缩液进行冻干。

LaAl法测定内毒素低于0.1μE/μg的RMUBcl-XL。

我们建议在打开之前将这个小瓶简单地离心,以将内容物带到底部。在含0.1% BSA的无菌蒸馏水或含水缓冲液中重组,浓度为0.1-1.0mg/mL。原料溶液应分摊到工作等分试样中,并储存在小于20℃的温度下,应在适当的缓冲溶液中进一步稀释。

 

AAA序列SqnRelvVVD FLSYKLQKG

产品描述

概述

 

Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays a role in the signal transduction pathway of the FAS-Ligand. Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. It is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. It has cell death repressor activity and therefore acts as a survival protein. The murine Bcl-xL shares 97 % and 99 % a.a. sequence identity with human and rat Bcl-xL, respectively.

使用说明

 

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

 

 

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 97 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Test in Process.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4, 5 % Trehalose.
Endotoxin Less than 0.1 EU/μg of rMuBcl-xL as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R