RepSox-干细胞-试剂-生物在线
RepSox

RepSox

商家询价

产品名称: RepSox

英文名称: RepSox

产品编号: SM-0006-0010

产品价格: 0

产品产地: 以色列

品牌商标: Biological industries(BI)

更新时间: null

使用范围: null

上海逍鹏生物科技有限公司
  • 联系人 : 市场部
  • 地址 : 上海市浦东新区祖冲之路1505弄80号1幢3楼
  • 邮编 : 200120
  • 所在区域 : 上海
  • 电话 : 189****5545
  • 传真 : 021-58777053
  • 邮箱 : Never.huang@xpbiomed.com

 

Product Description


RepSox is a potent and selective inhibitor of the TGF-β type 1 receptor (TGFβRI)/ALK5 that exhibits cell permeability and specifically inhibits ALK5 autophosphorylation with IC50 of 4 nM. When used in conjunction with CHIR99021 (Cat. No. SM-0001-0010), LDN193189 (Cat. No. SM-0005-0010), and Y27632 (Cat. No. SM-0013-0010), among others, RepSox aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs) (Pagliuca, et al.). RepSox has also been shown to contribute to the reprogramming of mouse embryonic fibroblasts to iPSCs (Subramanyam, et al.), in addition to the induction of human fibroblasts into neuronal cells for research on Alzheimer’s disease (Hu, et al). 
 

Product Synonyms:

ALK5 inhibitor II, ALK5 Inhibitor, ALK5i, E-616452, SJN2511

Constructed from renowned protocols, Biological Industries selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.

 

 产品官网链接:https://www.bioind.com/worldwide/repsox/

想了解更多种类的小分子,请点击官网:https://www.bioind.com/worldwide/products/stem-cell-research/small-molecules/