PPAR Delta 小鼠单克隆抗体(2F9)
产品名称： PPAR Delta 小鼠单克隆抗体(2F9)
英文名称： PPAR Delta Mouse monoclonal antibody (2F9)
产品编号： LPA35807
产品价格： null
产品产地： 中国
品牌商标： Ablepscience
更新时间： null
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- 所在区域 : 湖北
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产品索引
产品数据
货号 LPA35807 文献 详细请查看官网 产品名称 PPAR Delta mouse Monoclonal Antibody(2F9) 中文名称 PPAR Delta 小鼠单克隆抗体(2F9) 规格 100ug 适应种属 Human,Rat,Mouse 纯化方法 The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. UniProt ID 浓度 1mg/ml 宿主 Mouse 克隆性 Monoclonal 亚型 免疫原 Recombinant Protein of PPAR Delta of PPAR Delta 分子量 验证应用 IF,IHC-p 验证应用 Liquid 建议稀释比例 IF: 1:50-200 IHC 1:100-200 存储条件 -20°C/1 year 偶联物 Unconjugated 储存溶液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 运输条件 所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。 注意事项 该产品仅供科研使用
背景介绍
peroxisome proliferator activated receptor delta(PPARD) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this