西安瑞禧生物科技有限公司自主研发的多聚赖氨酸系列产品具有稳定性高，溶解性高，性价比高等优势

ε-聚赖氨酸的作用机理主要表现在如下3个方面：
(1)作用于细胞壁和细胞膜系统；
(2)作用于遗传物质或遗传微粒结构；
(3)作用于酶或功能蛋白。
ε-聚赖氨酸机理主要表现在破坏微生物的细胞膜结构，引起细胞的物质、能量和信息传递中断，最终导致细胞死亡

TAMRA-Oligoarginine
(biochemistry)A relatively shortpolyarginine, especially one used to enhance cellular delivery of a drug

The involvement of vesicular formation processes in the membrane transduction and nuclear transport of oligoarginine is currently a subject of controversy. In this report, a novel quantitative method which allows for the selective measurement of membrane transduction excluding concurrent endocytosis was used to determine the effects of temperature, endosomal acidification, endosomolysis, and several known inhibitors of endocytic pathways on the internalization of oligoarginine. The results show that, unlike endocytosis, transduction of oligoarginine was not affected by incubation at 16C as compared to the 37C control, and was only partially inhibited at 4C incubation. Additionally, membrane transduction was not inhibited to the same extent as endocytosis following treatment with ammonium chloride, hypertonic medium, amiloride, or filipin. The endosomolytic activity of oligoarginine was investigated by examining the leakage of FITC-dextran into the cytosolic compartment, which was not higher in the presence of oligoarginine. Furthermore, ammonium chloride showed no effect on the nuclear transport of oligoarginine. The data presented in this report indicate that membrane transduction is likely to occur at the plasma membrane without the formation of membrane vesicles, and the nuclear localization involves membrane transduction, rather than endocytosis of oligoarginine.

西安瑞禧生物科技有限公司可提供相关产品：
L-Lysine homopolymer hydrobromide 多聚-L-赖氨酸氢溴酸盐 25988-63-0
Oligoarginine 寡聚精氨酸
Epsilon-polylysine EPSILON-多聚赖氨酸 28211-04-3
Poly-L-lysine 聚赖氨酸 Cas 25104-18-1
Oligoarginine-FITC Labeled  
FITC-Oligoarginine
TAMRA-Oligoarginine
Oligoarginine-Tamra Labeled
Poly-L-lysine-FITC Labeled  25988-63-0
FITC-Poly-L-lysine
FITC-PLL
Epsilon-poly-L-lysine-FITC Labeled PSILON-多聚赖氨酸-FITC
Poly-L-arginine 聚 L-精氨酸盐酸盐 CAS: 26982-20-7
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