Anti-SAA1/Serum Amyloid A/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SAA1/Serum Amyloid A/FITC Conjugated抗体

Anti-SAA1/Serum Amyloid A/FITC Conjugated抗体


产品名称: Anti-SAA1/Serum Amyloid A/FITC Conjugated抗体

英文名称: Anti-SAA1/Serum Amyloid A/FITC

产品编号: YB--19359R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
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 Anti-SAA1/Serum Amyloid A/FITC Conjugated抗体

产品编号 YB-19359R-FITC
英文名称 Anti-SAA1/Serum Amyloid A/FITC
中文名称 FITC标记的血清淀粉样蛋白A抗体
别    名 amyloid A, serum; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA2; Serum amyloid A protein; serum amyloid A-1 protein; serum amyloid A1; TP53I4; Tumor protein p53 inducible protein 4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAA1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012]

Major acute phase reactant. Apolipoprotein of the HDL complex. 

Homohexamer; dimer of trimers. Can form amyloid fibrils after partial proteolysis; the native, undenatured protein does not form amyloid fibrils (in vitro). Apolipoprotein of the HDL complex. Binds to heparin.

Subcellular Location:

Tissue Specificity:
Expressed by the liver; secreted in plasma (at protein level).

Post-translational modifications:
This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.

Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Elevated serum SAA1 protein levels may be associated with lung cancer.

Database links:

Entrez Gene: 6288 Human

Entrez Gene: 20208 Mouse

Omim: 104750 Human

SwissProt: P0DJI8 Human

SwissProt: P05366 Mouse

Unigene: 632144 Human

Unigene: 148800 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.