Anti-Claudin 8/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Claudin 8/FITC Conjugated抗体

Anti-Claudin 8/FITC Conjugated抗体


产品名称: Anti-Claudin 8/FITC Conjugated抗体

英文名称: Anti-Claudin 8/FITC

产品编号: YB-5016R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
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 Anti-Claudin 8/FITC Conjugated抗体

产品编号 YB-5016R-FITC
英文名称 Anti-Claudin 8/FITC
中文名称 FITC标记的紧密连接蛋白8抗体
别    名 CLDN8; Claudin8; CLD 8; CLD8; CLDN 8; Claudin 8; Claudin-8; CLD8_HUMAN; OTTHUMP00000101915.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Claudin 8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]

Plays a major role in tight junction-specific obliteration of the intercellular space.

Subcellular Location:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in the epididymis, mainly in the caput segment.

Belongs to the claudin family.

Database links:

Entrez Gene: 9073 Human

Entrez Gene: 54420 Mouse

Entrez Gene: 304124 Rat

Omim: 611231 Human

SwissProt: P56748 Human

SwissProt: Q9Z260 Mouse

Unigene: 162209 Human

Unigene: 25836 Mouse

Unigene: 79297 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.