产品索引
        

        
产品数据 
        

          

            

              

                货号
              
              
LPA28768
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
Epithelial Membrane Antigen(MUC1) (ABT-EMA) mouse Monoclonal Antibody
            
            

              

                中文名称
              
              
Epithelial Membrane gen(MUC1) (ABT-EMA) 小鼠单克隆抗体
            
            

              
规格
              
100ug
              
适应种属
              
Human
            
            

              

                纯化方法
              
              
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
              

                UniProt ID
              
              

                
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse/IgG2b
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              
IgG2b
            
            

              

                免疫原
              
              
Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1) 
              

                分子量
              
              

            
            

              

                验证应用
              
              
IHC-p,WB
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
IHC-p 1:100-500，WB 1:500-2000
              

                存储条件
              
              
-20°C/1 year
            
            

              

                偶联物
              
              
Unconjugated 
              

                储存溶液
              
              
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
mucin 1, cell surface associated(MUC1)  Homo sapiens    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp

        
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