产品索引
        

        
产品数据 
        

          

            

              

                货号
              
              
LPA26374
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
CD45 mouse Monoclonal Antibody(12A9)
            
            

              

                中文名称
              
              
CD45 小鼠单克隆抗体(12A9)
            
            

              
规格
              
100ug
              
适应种属
              
Human
            
            

              

                纯化方法
              
              
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
              

                UniProt ID
              
              

                
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              

            
            

              

                免疫原
              
              
Synthetic Peptide of CD45 
              

                分子量
              
              

            
            

              

                验证应用
              
              
IF,WB,IHC-p,
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
IF: 1:50-200 WB: 1:2000 IHC 1:50-300
              

                存储条件
              
              
-20°C/1 year
            
            

              

                偶联物
              
              
Unconjugated 
              

                储存溶液
              
              
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
protein tyrosine phosphatase, receptor type C(PTPRC)    Homo sapiens    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc

        
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