产品索引
        

        
产品数据 
        

          

            

              

                货号
              
              
LPA31515
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
Insulin (ABT-INS) mouse Monoclonal Antibody
            
            

              

                中文名称
              
              
Insulin (ABT-INS) 小鼠单克隆抗体
            
            

              
规格
              
100ug
              
适应种属
              
Human
            
            

              

                纯化方法
              
              
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
              

                UniProt ID
              
              

                
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse/IgG2b
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              
IgG2b
            
            

              

                免疫原
              
              
Synthesized peptide derived from human Insulin 
              

                分子量
              
              

            
            

              

                验证应用
              
              
IHC-p
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
IHC-p 1:100-500
              

                存储条件
              
              
-20°C/1 year
            
            

              

                偶联物
              
              
Unconjugated 
              

                储存溶液
              
              
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
insulin(INS)    Homo sapiens    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

        
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