Collagen IV 小鼠单克隆抗体(8G3)
产品名称： Collagen IV 小鼠单克隆抗体(8G3)
英文名称： Collagen IV Mouse monoclonal antibody (8G3)
产品编号： LPA27290
产品价格： null
产品产地： 中国
品牌商标： Ablepscience
更新时间： null
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产品索引
产品数据
货号 LPA27290 文献 详细请查看官网 产品名称 Collagen IV mouse Monoclonal Antibody(8G3) 中文名称 Collagen IV 小鼠单克隆抗体(8G3) 规格 100ug 适应种属 Human,Mouse,Rat 纯化方法 The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen. UniProt ID 浓度 1mg/ml 宿主 Mouse 克隆性 Monoclonal 亚型 免疫原 Synthetic Peptide of Collagen IV 分子量 验证应用 IHC-p 验证应用 Liquid 建议稀释比例 IHC-p 1:50-300 存储条件 -20°C/1 year 偶联物 Unconjugated 储存溶液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 运输条件 所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。 注意事项 该产品仅供科研使用
背景介绍
collagen type IV alpha 1 chain(COL4A1) Homo sapiens This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],