Adrenocorticotropin(ACTH) (ABT-ACTH) 小鼠单克隆抗体
产品名称： Adrenocorticotropin(ACTH) (ABT-ACTH) 小鼠单克隆抗体
英文名称： Adrenocorticotropin(ACTH) (ABT-ACTH) Mouse monoclonal antibody
产品编号： LPA24386
产品价格： null
产品产地： 中国
品牌商标： Ablepscience
更新时间： null
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产品索引
产品数据
货号 LPA24386 文献 详细请查看官网 产品名称 Adrenocorticotropin(ACTH) (ABT-ACTH) mouse Monoclonal Antibody 中文名称 Adrenocorticotropin(ACTH) (ABT-ACTH) 小鼠单克隆抗体 规格 100ug 适应种属 Human 纯化方法 The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. UniProt ID 浓度 1mg/ml 宿主 Mouse/IgG1 克隆性 Monoclonal 亚型 IgG1 免疫原 Synthesized peptide derived from human Adrenocorticotropin(ACTH) 分子量 验证应用 IHC-p 验证应用 Liquid 建议稀释比例 WB 500-2000 IHC-p 1:100-500 存储条件 -20°C/1 year 偶联物 Unconjugated 储存溶液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 运输条件 所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。 注意事项 该产品仅供科研使用
背景介绍
proopiomelanocortin(POMC) Homo sapiens This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. The