产品索引
        

        
产品数据 
        

          

            

              

                货号
              
              
LPA24225
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
Acetyl P53(K382) mouse Monoclonal Antibody(5H10)
            
            

              

                中文名称
              
              
Acetyl P53(K382) 小鼠单克隆抗体(5H10)
            
            

              
规格
              
100ug
              
适应种属
              
Human,Mouse,Rat
            
            

              

                纯化方法
              
              
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
              

                UniProt ID
              
              

                
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              

            
            

              

                免疫原
              
              
Synthetic Peptide of human Acetyl P53(K382) 
              

                分子量
              
              

            
            

              

                验证应用
              
              
IHC-p
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
WB 500-2000 IHC-p 1:50-300
              

                存储条件
              
              
-20°C/1 year
            
            

              

                偶联物
              
              
Unconjugated 
              

                储存溶液
              
              
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
tumor protein p53(TP53) Homo sapiens    This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

        
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