产品索引
        
Mercurial-insensitive water channel;MIWC;AQP-4
        
产品数据 
        

          

            

              

                货号
              
              
LPMA10269
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
Anti Aquaporin-4 mouse monoclonal antibody
            
            

              

                中文名称
              
              
 Aquaporin-4 小鼠单克隆抗体
            
            

              
规格
              
100ug
              
适应种属
              
Human
            
            

              

                纯化方法
              
              
Protein G purified from mice ascites
              

                UniProt ID
              
              

                P55087
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              
IgG 1
            
            

              

                免疫原
              
              
Cys+SMNPARSFGP;Cys+TINWGGSENPLP+KLH 
              

                分子量
              
              
35 kDa
            
            

              

                验证应用
              
              
Elisa,IHC
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
Elisa:1:1000~5000,IHC:1:50~100
              

                存储条件
              
              
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
            
            

              

                偶联物
              
              
Unconjugate 
              

                储存溶液
              
              
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
Forms a water-specific channel (PubMed:7559426, PubMed:8601457, PubMed:19383790). Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability (By similarity)

        
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