CASP5 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： CASP5 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： CASP5 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00000838-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human CASP5 protein.
- Immunogen:
- CASP5 (ADR83176.1, 1 a.a. ~ 418 a.a) full-length human protein.
- Sequence:
- MFKGILQSGLDNLVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDAKIEDKALILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPHEEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDILGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Application Image
- Western Blot (Transfected lysate)
- Detection Antibody
- Entrez GeneID:
- 838
- GeneBank Accession#:
- HQ258422.1
- Protein Accession#:
- ADR83176.1
- Gene Name:
- CASP5
- Gene Alias:
- ICE(rel)III,ICEREL-III,ICH-3,MGC141966
- Gene Description:
- caspase 5, apoptosis-related cysteine peptidase
- Omim ID:
- 602665
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000045729,TY protease,caspase 5,caspase 5, apoptosis-related cysteine protease
- Related Disease
- Adenocarcinoma
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C, Chronic
- Hodgkin Disease
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Sclerosis
- Occupational Diseases
- Ovarian cancer
- Ovarian Neoplasms
- Prostatic Neoplasms
- Retinoblastoma
- Tobacco Use Disorder
- Waldenstrom Macroglobulinemia
- Werner syndrome