ATAT1 小鼠单克隆抗体
产品名称： ATAT1 小鼠单克隆抗体
英文名称： ATAT1 Mouse monoclonal antibody
产品编号： LPMA10275
产品价格： null
产品产地： 中国
品牌商标： Ablepscience
更新时间： null
使用范围：
- 联系人 :
- 地址 : 武汉东湖新技术开发区汤逊湖北路36号新能源研发基地3号楼3层314室
- 邮编 : 430075
- 所在区域 : 湖北
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- 邮箱 : sale@apescience.cn;3055949650@qq.com
产品索引
Alpha-tubulin N-acetyltransferase 1
产品数据
货号 LPMA10275 文献 详细请查看官网 产品名称 Anti ATAT1 mouse monoclonal antibody 中文名称 ATAT1 小鼠单克隆抗体 规格 100ug 适应种属 Human 纯化方法 Protein G purified from mice ascites UniProt ID Q5SQI0 浓度 1mg/ml 宿主 Mouse 克隆性 Monoclonal 亚型 IgG1 免疫原 MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRP 分子量 47 kDa 验证应用 WB,IF,IHC 验证应用 Liquid 建议稀释比例 WB:1:1000~4000;IF:1:100~200,IHC:1:50~100 存储条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt. 偶联物 Unconjugate 储存溶液 PBS, pH7.4, containing 0.05% proclin300, 50% glycerol. 运输条件 所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。 注意事项 该产品仅供科研使用
背景介绍
leads to drug resistance for microtubule-targeting drugs such as taxol and celastrol by downregulation of p53. DDX53 promotes autophagy by increasing expression of ATG5 via direct binding to the promoter of ATG5 in breast cancer cells. In addition, DDX53 shows co-expression with CD133, a cancer stemness marker, and is served as a new key regulator of cancer stem cell-like properties in taxol-resistant melanoma. Many evidences suggest that DDX53 is one of the attractive targets for developing anti-cancer drugs, there have not been reports concerning the role of DDX53 in cervix cancer.DDX53 (DEAD-Box Helicase 53) is a Protein Coding gene. Diseases associated with DDX53 includeColonic DiseaseandGastric Adenosquamous Carcinoma. Gene Ontology (GO) annotations related to this gene includenucleic acid bindingandATP-dependent RNA helicase activity.