IRAK1 (Human) Recombinant Protein
产品名称: IRAK1 (Human) Recombinant Protein
英文名称: IRAK1 (Human) Recombinant Protein
产品编号: P5565
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human IRAK1 (NP_001560.2, 194 a.a. - 712 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 83
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf21) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 100 % by SDS-PAGE/CBB staining
- Activity:
- The activity was determined by IMAPTM assay. The enzyme was incubated with fluorescein labeled peptide and phosphorylation was detected by IMAPTM technology (fluorescence polarization). Substrate: SRPKtide. ATP: 100 uM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 3654
- Protein Accession#:
- NP_001560.2
- Gene Name:
- IRAK1
- Gene Alias:
- IRAK,pelle
- Gene Description:
- interleukin-1 receptor-associated kinase 1
- Omim ID:
- 300283
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000026014,OTTHUMP00000026020,Pelle homolog
- Related Disease
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Calcinosis
- Carcinoma
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Chronic Disease
- Coronary Artery Disease
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- HIV Infections
- Hypertension
- Kidney Diseases