Anti-Active Gαs-GTP Mouse Monoclonal Antibody-抗体-抗体-生物在线
武汉纽斯特生物技术有限公司
Anti-Active Gαs-GTP Mouse Monoclonal Antibody

Anti-Active Gαs-GTP Mouse Monoclonal Antibody

商家询价

产品名称： Anti-Active Gαs-GTP Mouse Monoclonal Antibody

英文名称： Anti-Active Gαs-GTP Mouse Monoclonal Antibody

产品编号： 26906

产品价格： null

产品产地： 美国

品牌商标： NewEastbio

更新时间： null

使用范围： IP, IHC

武汉纽斯特生物技术有限公司
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Active Gαs-GTP [26906]
[30 µL]		  

Catalog Number:  26906
Gene Symbol:  Gnas
Description:   Anti-Active Gαs-GTP Mouse Monoclonal Antibody
Background:   Heterotrimeric G proteins are critical cellular signal transducers. Gαs represents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases.
Immunogen:   Recombinant full length protein of active Gαs
Applications:   IP, IHC
Recommended Dilutions:   1 µg for 1~2 mg total cellular proteins for IP;
                                                   1:100 dilution for IHC
Concentration:   1 mg/ml
Host:   mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-active Gαs antibody recognizes active Gαs of vertebrates
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Immunoprecipitation/Western blot:  
Gαs activation assay. Purified Gαs proteins were loaded as a control (lanes 1) or immunoprecipitated after treated with GDP (lane 2) or GTPγS (lane 3). Immunoprecipitation was done with the anti-active Gαs monoclonal antibody (Cat. No. 26906). Immunoblot was with an anti- Gαs monoclonal antibody (Cat. No. 26006).

 

Publications:
1.  Glucocorticoid acts on a putative G protein-coupled receptor to rapidly regulate the activity of NMDA receptors in hippocampal neurons
    Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E747-58
2.  CRH activation of different signaling pathways results in differential calcium signaling in human pregnant myometrium before and during labor
    J Clin Endocrinol Metab. 2012 Oct;97(10):E1851-61
3.  Estrogenic action on arterial smooth muscle: permissive for maintenance of CRHR2 expression
    Endocrinology. 2012 Apr;153(4):1915-24
4.  Corticotropin-releasing hormone stimulates mitotic kinesin-like protein 1 expression via a PLC/PKC-dependent signaling pathway in hippocampal neurons
    Mol Cell Endocrinol. 2012 Oct 15;362(1-2):157-64
5.   Rapid actions of xenoestrogens disrupt normal estrogenic signaling
     Steroids Volume 81, March 2014, Pages 36–42
6.   Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation
     Hum. Mol. Genet. (2014)