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Anti-CKMT1成都正能生物技术有限责任公司

性能参数

产品名称: Anti-CKMT1
抗体货号: 200627
产品规格: 100ul
级    别: Affinity purified
产品产地: 成都正能生物
品牌商标: Zen BioScience
价    格: 2780元
抗原来源: Human
抗体来源: Mouse
适用物种: H,M
Isotype:IgG1
应用范围: WB
更新时间: 2019/7/6 12:15:00
详细资料:  实验方法技术资料
浏览人数:479
诚信指数:121点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

成都正能生物技术有限责任公司
地址:
中国成都高新区科园南路爱斯特大厦
邮编:
610200
电话:
028-85739596
传真:
+86-028-85739596
联系人:
小能
所在区域:
四川·成都
邮件:
公司展台:
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产品详细描述

Size  100ug

Cat code  200627

Species Cross-reactivity  H,M

Key Application  WB

Host  Mouse

Antibody type  Monoclonal antibody

Purified method  Affinity purified

Isotype  IgG1

Molecular Weight  47kDa

Sensitivity  This antibody detects endogenous levels of CKMT1 and does not cross-react with related proteins.

Immunogen  Purified recombinant human CKMT1 protein fragments expressed in E.coli.

UniProt Number  P12532

GeneBank ID  NM_020990.3

Subcellular location  Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.

Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Altername  Acidic-type mitochondrial creatine kinase Short name=Mia-CK Ubiquitous mitochondrial creatine kinase Short name=U-MtCK

Gene_symbol  CKMT; CKMT1; UMTCK; CKMT1A

Summary  Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

UniPort summary Function  Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Application Images :  

Western blot detection of CKMT1 in Mouse Colon,293&A431 cell lysates using CKMT1 antibody (1:1000 diluted). Predicted band size:47KDa Observed band size:47KDa.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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