Anti-Beclin 1-抗体-抗体-生物在线
Anti-Beclin 1

Anti-Beclin 1

商家询价

产品名称: Anti-Beclin 1

英文名称:

产品编号: 200675

产品价格: null

产品产地: 成都正能生物

品牌商标: Zen BioScience

更新时间: null

使用范围: WB

成都正能生物技术有限责任公司
  • 联系人 :
  • 地址 : 中国成都高新区科园南路爱斯特大厦
  • 邮编 : 610200
  • 所在区域 : 四川
  • 电话 : 180****2350
  • 传真 : +86-028-85739596
  • 邮箱 : sales@zen-bioscience.com

Size  100ug

Cat code  200675

Species Cross-reactivity  H,M

Key Application  WB

Host  Mouse

Antibody type  Monoclonal antibody

Purified method  Affinity purified

Isotype  IgG1

Molecular Weight  55kDa

Sensitivity  This antibody detects endogenous levels of BECN1 and does not cross-react with related proteins.

Immunogen  Purified recombinant human BECN1 protein fragments expressed in E.coli.

UniProt Number  Q14457

GeneBank ID  NM_003766.3

Subcellular location  Golgi apparatus ? trans-Golgi network membrane; Peripheral membrane protein.

Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Altername  Coiled-coil myosin-like BCL2-interacting protein Protein GT197

Gene_symbol  ATG6; VPS30; beclin1

Summary  Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).

UniPort summary Function  Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Application Images :  

Western blot detection of BECN1 in Mouse brain,A431&Hela cell lysates using BECN1 antibody (1:1000 diluted). Predicted band size:52KDa. Observed band size:55KDa