CXCL5,上皮中性粒细胞活化肽78抗体

产品编号HZ-2549R
英文名称CXCL5
中文名称上皮中性粒细胞活化肽78抗体
别 名AMCFII; C-X-C motif chemokine 5; Cxcl5; CXCL5_HUMAN; ENA-78(1-78); ENA-78(9-78); ENA78; Epithelial derived neutrophil activating peptide 78; Epithelial derived neutrophil activating protein 78; Epithelial-derived neutrophil-activating protein 78; GCP2; LIX; Neutrophil activating peptide ENA 78; Neutrophil-activating peptide ENA-78; SCYB5; Scyb6; Small inducible cytokine B5; Small inducible cytokine subfamily B member 5; Small-inducible cytokine B5.
说 明 书0.1ml 0.2ml
研究领域免疫学 生长因子和激素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,
CXCL5,上皮中性粒细胞活化肽78抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量8/9kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse CXCL5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CXCL5,上皮中性粒细胞活化肽78抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. [provided by RefSeq].

Function:
May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.

Subcellular Location:
Secreted.

Post-translational modifications:
GCP-2(1-78) and GCP-2(9-78) are produced by proteolytic cleavage after secretion from fibroblasts and epithelial cells. GCP-2(9-78) is the most prominent form. A number of additional N-terminal (processed between pos. 41 and 48) and C-terminal (processed between pos. 118 and 132) processed forms have been identified, probably also representing intermediate states.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

Gene ID:
20311

Database links:
Entrez Gene: 6374 Human
Entrez Gene: 20311 Mouse
Omim: 600324 Human
SwissProt: P42830 Human
SwissProt: P50228 Mouse
Unigene: 89714 Human
Unigene: 4660 Mouse

CXCL5,上皮中性粒细胞活化肽78抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.