COMMD4,COMM结构域蛋白4抗体

产品编号HZ-8037R
英文名称COMMD4
中文名称COMM结构域蛋白4抗体
别 名COMD4_HUMAN; COMM domain-containing protein 4; COMMD4.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Horse,
COMMD4,COMM结构域蛋白4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from Human COMMD4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COMMD4,COMM结构域蛋白4抗体PubMedPubMed
产品介绍background:
COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Down-regulates activation of NF-kappa-B.

Function:
Down-regulates activation of NF-kappa-B.

Subunit:
Interacts (via COMM domain) with COMMD1 (via COMM domain).

Tissue Specificity:
Ubiquitous.

COMMD4,COMM结构域蛋白4抗体Similarity:
Contains 1 COMM domain.

Gene ID:
54939

Database links:
Entrez Gene: 54939 Human
SwissProt: Q9H0A8 Human
Unigene: 351327 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Tissue/cell: rat testis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-COMMD4 Polyclonal Antibody, Unconjugated(HZ-8037R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining