CYP4B1,细胞色素P450 4B1抗体

产品编号HZ-14156R
英文名称CYP4B1
中文名称细胞色素P450 4B1抗体
别 名CP4B1_HUMAN; CYP4B1; CYPIVB1; Cytochrome P450 4B1; Cytochrome P450 family 4 subfamily B polypeptide 1; Cytochrome P450 subfamily IVB polypeptide 1; Cytochrome P450-HP; Microsomal monooxygenase; P450HP.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 细胞生物 信号转导 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
CYP4B1,细胞色素P450 4B1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CYP4B1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CYP4B1,细胞色素P450 4B1抗体PubMedPubMed
产品介绍background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Subcellular Location:
Endoplasmic reticulum membrane. Microsome membrane.

Tissue Specificity:
Detected in the liver and lung (at protein level).

Similarity:
Belongs to the cytochrome P450 family.

Gene ID:
1580

CYP4B1,细胞色素P450 4B1抗体Database links:
Entrez Gene: 1580 Human
Omim: 124075 Human
SwissProt: P13584 Human
Unigene: 436317 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.