GALR1,甘丙肽受体1抗体

产品编号HZ-9927R
英文名称GALR1
中文名称甘丙肽受体1抗体
别 名GAL1R; galanin receptor 1; Galanin receptor; Galanin receptor type 1; GALNR; GALNR1; GALR1; GALR1_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 神经生物学 信号转导 生长因子和激素 通道蛋白 G蛋白偶联受体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
GALR1,甘丙肽受体1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量39kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human GALR1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
GALR1,甘丙肽受体1抗体PubMedPubMed
产品介绍background:
GALR1 is a G-protein-coupled receptor for the neuropeptide galanin that influences endocrine secretions, intestinal motility, memory, weight, and pain perception. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, and in peripheral sites such as the small intestine and heart. The rat galanin receptor cDNA cloned from an insulinoma cell line is a predicted 346-amino acid G protein-coupled receptor with 92% homology to the human GALR1.

Function:
Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

Subcellular Location:
Cell Membrane; multi pass membrane protein

Post-translational modifications:
Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:
Entrez Gene: 2587 Human
Entrez Gene: 14427 Mouse
Omim: 600377 Human
SwissProt: P47211 Human
SwissProt: P56479 Mouse
Unigene: 272191 Human

GALR1,甘丙肽受体1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.