T4/L-Thyroxine,甲状腺素T4抗体

产品编号HZ-0706R
英文名称T4/L-Thyroxine
中文名称甲状腺素T4抗体
别 名Thyroxine 4; T4; Tg4; L-Thyroxine; Thyroxine; 3,3′,5,5″-Tetraiodo-L-thyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine.
说 明 书0.1ml 0.2ml
研究领域信号转导 生长因子和激素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
T4/L-Thyroxine,甲状腺素T4抗体产品应用ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量0.77687kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from hu T4/L-Thyroxine
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
T4/L-Thyroxine,甲状腺素T4抗体PubMedPubMed
产品介绍background:
Hormone produced by the thyroid glands to regulate metabolism by controlling the rate of oxidation in cells. Cases of hypothyroidism, where the gland is insufficiently active, can be treated by administration of thyroxine or a combination of thyroxine and triiodothyronine. L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.

Subcellular Location:
Secreted

Gene ID:
51-48-9

T4/L-Thyroxine,甲状腺素T4抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

甲状腺素（Thyroxine, T4）是甲状腺分泌最多的一种激素，血液中的T4全部由甲状腺分泌而来，故血液中T4的浓度能很好地反应甲状腺功能状态。正常情况下，血液中60%的T4与甲状腺素结合球蛋白（TBG）结合，30%与甲状腺素结合前蛋白（TBPA）结合，其余约10%与白蛋白结合，仅约0.03-0.04%呈游离状态。由于T4与TBG亲合力较高，所以血中T4的水平最易受到TBG的影响。