Reg3 gamma,胰岛β细胞生长因子Reg IIIγ抗体

产品编号HZ-4912R
英文名称Reg3 gamma
中文名称胰岛β细胞生长因子Reg IIIγ抗体
别 名Reg III gamma; REG3G_HUMAN; Reg3 gamma; Reg3gamma; Reg-3gamma; Regenerating islet-derived protein 3-gamma; REG-3-gamma; Pancreatitis-associated protein 1B; PAP-1B; Pancreatitis-associated protein IB; PAP IB; Regenerating islet-derived protein III-gamma; Reg III-gamma.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
Reg3 gamma,胰岛β细胞生长因子Reg IIIγ抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Reg3 gamma
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Reg3 gamma,胰岛β细胞生长因子Reg IIIγ抗体PubMedPubMed
产品介绍background:
The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV, all of which share a common gene structure containing five introns and six exons. Members of the Reg family have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Reg lll(regenerating islet-derived 3 gamma), also known as pancreatitis-associated protein 1B, PAP1B, or UNQ429, is a 175 amino acid secreted protein that is expressed almost exclusively in pancreas, with low levels of expression in testis. Reg lll?functions as an antimicrobial protein involved in controlling bacterial proliferation and may be induced during acute pancreatitis. The gene encoding Reg lll?maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.

Function:
Might be a stress protein involved in the control of bacterial proliferation.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed almost exclusively in the pancreas. Also expressed in testis. Not found in small intestine.

Similarity:
Contains 1 C-type lectin domain.

Reg3 gamma,胰岛β细胞生长因子Reg IIIγ抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-Reg3 gamma Polyclonal Antibody, Unconjugated(HZ-4912R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining