NAP1L2,脑特异性蛋白BPX抗体

产品编号HZ-11172R
英文名称NAP1L2
中文名称脑特异性蛋白BPX抗体
别 名Brain specific gene BPX; BPX; Brain specific protein, X linked; MGC26243; Nucleosome assembly protein 1 like 2; NP1L2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域染色质和核信号 神经生物学 细胞粘附分子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
NAP1L2,脑特异性蛋白BPX抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human NAP1L2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
NAP1L2,脑特异性蛋白BPX抗体PubMedPubMed
产品介绍background:
Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons.

Function:
NAP1L2 is a member of the nucleosome assembly protein (NAP) family.

Subcellular Location:
Nuclear

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:
UniProtKB/Swiss-Prot: Q9ULW6.1

NAP1L2,脑特异性蛋白BPX抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.