lipocalin 1/LCN1,脂质运载蛋白1抗体

产品编号HZ-11286R
英文名称lipocalin 1/LCN1
中文名称脂质运载蛋白1抗体
别 名LCN1; LCN1_HUMAN; Lipocalin 1 (protein migrating faster than albumin, tear prealbumin); Lipocalin 1 like 2; Lipocalin-1; lipocalin 1; PMFA; Tear lipocalin; Tear prealbumin; Tlc; TP antibody VEG protein; VEGP; Von Ebner gland protein.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 泛素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
lipocalin 1/LCN1,脂质运载蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human lipocalin 1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
lipocalin 1/LCN1,脂质运载蛋白1抗体PubMedPubMed
产品介绍background:
Lipocalin-1 is a secretory protein that is highly expressed in fluids covering epithelial surfaces such as tears and respiratory secretions. This major lipid-binding protein in tears is also called tear lipocalin (TL) and von Ebner’s gland protein (VEG), as it is also a major secretion of these lingual salivary glands. In addition to lacrimal glands and lingual glands, Lipocalin-1 is secreted by nasal mucosal glands, secretory glands of the tracheobronchial tract, sweat glands, mammary glands, adrenal gland, prostate, thymus, testis and corticotrophs of the pituitary gland. Specifically, Lipocalin-1 functions to stabilize the lipid film of human tear fluid by removing harmful lipids from the human corneal surface and delivering them to the aqueous phase of tears. Lipocalin-1 may also function as a transporter of hydrophobic molecules such as bitter substances on the tongue.

Function:
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.

Subunit:
Homodimer. Binds to LMBR1L which may mediate its endocytosis.

Subcellular Location:
Secreted.

lipocalin 1/LCN1,脂质运载蛋白1抗体Tissue Specificity:
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

Similarity:
Belongs to the calycin superfamily. Lipocalin family.

Database links:
Entrez Gene: 3933 Human
Omim: 151675 Human
SwissProt: P31025 Human
Unigene: 530311 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.