CELSR3,表皮生长因子样蛋白1抗体

产品编号HZ-11460R
英文名称CELSR3
中文名称表皮生长因子样蛋白1/Flamingo homolog 1抗体
别 名Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; CDHF11; CELR3_HUMAN; CELSR3; EGF-like protein 1; EGFL1; Epidermal growth factor-like protein 1; Flamingo; Flamingo homolog 1; FMI1; HFMI1; MEGF2; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 细胞粘附分子 细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
CELSR3,表皮生长因子样蛋白1抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量354kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Flamingo homolog 1 (1601-1700aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CELSR3,表皮生长因子样蛋白1抗体PubMedPubMed
产品介绍background:
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]

Function:
Receptor that may have an important role in cell/cell signaling during nervous system formation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 9 cadherin domains.
Contains 8 EGF-like domains.
Contains 1 GPS domain.
Contains 1 laminin EGF-like domain.
Contains 2 laminin G-like domains.

Gene ID:
92238

Database links:
Entrez Gene: 1951 Human
Omim: 604264 Human
SwissProt: Q9NYQ7 Human
Unigene: 55173 Human
Unigene: 631926 Human

CELSR3,表皮生长因子样蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.