Anti-MEK1 (E203K) Mouse Monoclonal Antibody-抗体-抗体-生物在线

Anti-MEK1 (E203K) Mouse Monoclonal Antibody

商家询价

产品名称： Anti-MEK1 (E203K) Mouse Monoclonal Antibody

英文名称： Anti-MEK1 (E203K) Mouse Monoclonal Antibody

产品编号： 26268

产品价格： null

产品产地：美国

品牌商标： NewEastbio

更新时间： null

使用范围： ELISA, WB, IHC

武汉纽斯特生物技术有限公司

联系人 :
地址 : 武汉市东湖新技术开发区光谷生物城B3-3栋2-3楼
邮编 : 430074
所在区域 : 湖北
电话 : 186****7297
传真 : 027-87561022
邮箱 : neweast3@126.com

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产品详情

MEK1 (E203K) [26268]
[100ul]

Catalog Number: 26268

Gene Symbol: MAP2K1; MAPKK1; MEK1; MKK1; PRKMK1

Description: Anti-MEK1 (E203K) Mouse Monoclonal Antibody

Background: MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK3/ERK1 and MAPK1/ERK2, thus activates the MAP pathway and regulates transcription. Abnormal of the MEK1 protein, including point mutations, are implicated in diseases such as cardiofaciocutaneous syndrome (CFC) and melanoma.

Immunogen: A synthetic peptide from the internal region of MEK1 which includes the mutation of E203K, human origin.

Applications: ELISA,WB

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes E203K mutant, but not wild-type MEK1 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Western blot:

Western blot analysis of recombinant MEK1 (E203K) and wildtype proteins. Purified His-tagged MEK1 (E203K) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with anti-MEK1 (E203K) monoclonal antibody (Cat. #26268).