Anti-ERBB2 (D769Y) Mouse Monoclonal Antibody-抗体-抗体-生物在线

Anti-ERBB2 (D769Y) Mouse Monoclonal Antibody

商家询价

产品名称： Anti-ERBB2 (D769Y) Mouse Monoclonal Antibody

英文名称： Anti-ERBB2 (D769Y) Mouse Monoclonal Antibody

产品编号： 26382

产品价格： null

产品产地：美国

品牌商标： NewEastBio

更新时间： null

使用范围： ELISA、IF、IHC

武汉纽斯特生物技术有限公司

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产品详情

ERBB2 (D769Y) [26382]
[100ul]

Catalog Number: 26382

Gene Symbol: ERBB2/HER2/Neu/c-Neu

Description: Anti-ERBB2 (D769Y) Mouse Monoclonal Antibody

Background: The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important critiria in clinic evaluating of the progression of breast cancer.

Immunogen: A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769Y, human origin.

Applications: ELISA, IF, IHC

Recommended Dilutions:
ELISA: 1:1000-1:2000
IF: 1:500-1:1000
IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes D769Y mutant, but not wild-type ERBB2 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Immunofluorescence:

Immunofluorescence of cells expressing ERBB2 proteins with anti-ERBB2 (D769Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-ERBB2 (D769Y) plasmid, pCDNA3-GFP-ERBB2 (WT) plasmid or pCDNA3-GFP-ERBB2 (D769H) plasmid, then fixed and stained with anti-ERBB2 (D769Y) monoclonal antibody (Cat. #26382).