Anti-IDH1 Rabbit Polyclonal Antibody-抗体-抗体-生物在线

Anti-IDH1 Rabbit Polyclonal Antibody

商家询价

产品名称： Anti-IDH1 Rabbit Polyclonal Antibody

英文名称： Anti-IDH1 Rabbit Polyclonal Antibody

产品编号： 21277

产品价格： null

产品产地：美国

品牌商标： NewEastBio

更新时间： null

使用范围： ELISA、WB、 IHC

武汉纽斯特生物技术有限公司

联系人 :
地址 : 武汉市东湖新技术开发区光谷生物城B3-3栋2-3楼
邮编 : 430074
所在区域 : 湖北
电话 : 186****7297
传真 : 027-87561022
邮箱 : neweast3@126.com

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产品详情

IDH1 [21277]
[100 µL]

Catalog Number: 21277

Gene Symbol: IDH1

Description: Anti-IDH1 Rabbit Polyclonal Antibody

Background: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.

Immunogen: Recombinant protein of human IDH1 (amino acids 1-240).

Applications: ELISA, WB, IHC

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:1000-1:5000
IHC: 1:50-1:500

Concentration: 1 mg/ml

Host: Rabbit

Format: Liquid

Clonality: Polyclonal

Isotype:

Purity: Purified from serum

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Anti-IDH1 antibody recognizes IDH1 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

Western blot:

Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat. #10198) was blotted with anti-IDH1 rabbit polyclonal antibody (Cat. # 21277).