磷酸化Rho GTP酶激活蛋白GAP抗体上海沪震实业有限公司

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产品名称: 磷酸化Rho GTP酶激活蛋白GAP抗体
英文名称: phospho-RACGAP1(Ser387)
抗体货号: hz-7767R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
更新时间: 2018/9/7 16:28:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-phospho-RACGAP1(Ser387) antibody

 

产品编号 hz-7767R
英文名称 phospho-RACGAP1(Ser387)
中文名称 ***酸化Rho GTP酶激活蛋白GAP抗体
别    名 RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387; GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.  
   
产品类型 ***酸化抗体 
研究领域 细胞生物  信号转导  转录调节因子  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387.:RI(p-S)GC 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Subunit:
Heterotetramer of two molecules each of RACGAP1 and KIF23.

Subcellular Location:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle.

Tissue Specificity:
Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase.

Similarity:
Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain.

SWISS:
Q9H0H5 

Gene ID:
29127 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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