磷酸化Ephrin B1抗体上海沪震实业有限公司

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产品名称: 磷酸化Ephrin B1抗体
英文名称: phospho-Ephrin B1 (Tyr317)
抗体货号: hz-10690R
产品规格: 100ul
级    别: , , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 1580元
抗原: IgG
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 见说明书
应用范围: WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
更新时间: 2018/9/10 10:34:00
详细资料:  实验方法技术资料
浏览人数:40
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-phospho-Ephrin B1 (Tyr317) antibody

 

产品编号 hz-10690R
英文名称 phospho-Ephrin B1 (Tyr317)
中文名称 ***酸化Ephrin B1抗体
别    名 phospho-Ephrin B1 (phospho Y317); Ephrin B (phospho Y317); p-Ephrin B (phospho Y317); phospho-Ephrin B1 (Tyr317); phospho-Ephrin B2(Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN.  
   
产品类型 ***酸化抗体 
研究领域 肿瘤  细胞生物  神经生物学  生长因子和激 
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Ephrin B1 around the phosphorylation site of Tyr317:PH(p-Y)EK 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Subunit:
Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein.

Tissue Specificity:
Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.

Post-translational modifications:
Membrane; single pass type I membrane protein.

Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.

SWISS:
P52799 

Gene ID:
1947 

Database links:

Entrez Gene: 1947 Human

Entrez Gene: 1948 Human

Entrez Gene: 13641 Mouse

Entrez Gene: 13642 Mouse

Entrez Gene: 25186 Rat

Omim: 300035 Human

Omim: 600527 Human

SwissProt: P52799 Human

SwissProt: P98172 Human

SwissProt: P52795 Mouse

SwissProt: P52800 Mouse

SwissProt: P52796 Rat

SwissProt: Q6P7B6 Rat

Unigene: 144700 Human

Unigene: 149239 Human

Unigene: 44398 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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